The park consists of 330 km2 (130 sq mi) of arid land, forest, and a soda-lake which covers as much as 200 km2(77 sq mi) of land during the wet season but is nearly nonexistent during the dry season.
 
Lake Manyara National Park is known for the flamingos that inhabit the lake. During the wet season they inhabit the edges of the lake in flocks of thousands but they are not so present during the dry season.

More than 400 species of birds inhabit the park and many remain throughout the year. Because of this Lake Manyara National Park is a good spot for bird watching. Visitors to the park can expect to see upwards of 100 different species of bird on any day.

Leopards, Masai lions, cheetahs, elephants, blue monkeys, dik-dik, gazelles, hippopotami, Masai giraffe, impala, zebras and many more wild animals inhabit this park and many can be seen throughout the year. There is a hippo pond at one end of the park where visitors can get out of their cars and observe from a safe distance. The leopards and lions are both known to lounge in the trees while not hunting for prey.

Lake Manyara National Park is located 126 km (78 mi) south west of Arusha and can be reached by car in an hour and a half. The park can also be reached easily from Babati the capital of Manyara Region. The park is also very close to Tarangire National Park.